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Take furosemide exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. To reduce nighttime urination, take furosemide early in the day unless otherwise directed by your doctor. It is important to take furosemide regularly to get the most benefit. Do not stop taking furosemide suddenly even if you feel better. Stopping suddenly could make your condition worse.


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Furosemide is a potent diuretic (water pill). Furosemide works by blocking the absorption of salt and fluid in the kidney tubules, causing a profound increase in urine output (diuresis). The diuretic effect of furosemide can cause body water and electrolyte depletion. Therefore, careful medical supervision is necessary during treatment.


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If you take one dose daily, take the missed dose as soon as you remember within 12 hours. If more than 12 hours have passed, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication. If you take more than one dose daily, take the missed dose up to 2 hours late. If more than 2 hours have passed, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.


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Patients allergic to sulfa may also be allergic to furosemide because of a similarity in the chemical structure of the medications. Furosemide should be avoided in kidney failure. Even though furosemide is important in treating excess fluid accumulation in patients with cirrhosis, sudden loss of fluid and electrolytes in these patients can worsen kidney function and even cause the patient to go into a coma. Furosemide can cause lowering of blood potassium, sodium, and magnesium levels. Low potassium and magnesium levels can lead to heart rhythm abnormalities, especially in patients already taking digoxin (Lanoxin). Please visit the digoxin (Lanoxin) site for further information. Blood uric acid levels can increase during furosemide treatment, but precipitation of acute gout is rare. Furosemide may increase the toxic effect of aminoglycoside antibiotics on the ear, especially in patients with kidney dysfunction. Furosemide reduces the kidney excretion of lithium and can lead to lithium toxicity. Furosemide may impair kidney function when administered together with aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Periodic blood tests are performed to monitor kidney function and electrolytes during treatment with furosemide.


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Commonly observed side effects are low blood pressure, and water and electrolyte depletion. Less common side effects include jaundice, ringing in ears (tinnitus), light sensitivity, rash, pancreatitis, nausea, abdominal pain, dizziness, anemia, and other blood disorders.


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Mongol Saga Episode VI – The Russian Border

AUTHOR’S NOTE: This is a repost of content I produced on the road in Europe, Russia and Mongolia for the Meridian Collective blog. I will repost one entry a day this week, leading up to new entries in my “Mongol Saga” series coming soon!

The hardest part of travelling across Europe before and during the Mongol Rally has been the clinging feeling of uncertainty – we don’t know whether our journey will be cut short in a matter of days or stretch for another month. We all still crave the latter, to roll into Ulaan Bataar in late August is still a magnificent dream to us. But as the days have turned into weeks and after a month of seeing the insides of many of Europe’s ancient cathedrals as well as its DMV-equivalents, and watching the rolling countryside through the window of our cramped yellow car, it is harder and harder to say we haven’t accomplished enough. I’m not sure we don’t already have enough stories to tell and that, given some of the difficulties we’ve experienced, we must push ourselves even further to reach some sort of catharsis, to feel like we’ve gone far enough.

Maybe that was the goal all along – to attain such a state of detachment that we would be equally open to returning home, tired and loose like a stretched out sweater, or heading still eastward through three giant countries that will toss us like rags, this way and that depending on the wind for another grueling month. Every day I ask myself if we are at the breaking point or just the halfway point.

The last few days have seen our odds of success (reaching the capital of Mongolia) twitch up and down like a seismograph needle during an earthquake. First our car broke down in Vilnius, Lithuania and we were on the side of the road in a light drizzle imagining the costs of repair overwhelming our travel budgets. Then the same day our car was miraculously running again, after the friendliest mechanics in Eastern Europe – at the Vilnius Nissan service station in case you are in the area – offered us parts and service free of charge. They changed both U-joints and two belts that were “too old” before making us leave without giving them more than a very sincere thank you. We spent that night admiring the bits of Vilnius we could scramble across, and the next day we were in Riga, Latvia doing the same dash through narrow cobblestoned streets. But, then our smoothly running car ran into the Russian border and we met even higher highs and lower lows than our mechanical troubles had presented us with.

We hit a line of semi-trucks around one in the afternoon, saw that it extended to the right at the intersection for half a kilometer and turned left, expecting to see the border around the bend. Instead we creeped along the line of trucks for several minutes until we found the end of the line for smaller vehicles, which was hundreds of cars long.

Two British Mongol Rally teams were already in line. One team, donning self-styled mullets, had already been turned away at the European border with Belarus for not having a visa, and so they were giving eastward a try again at the Russian border. By sundown, both teams were successfully inside Russia and we had gleaned a sizeable chunk of information from a middle-aged German who found that sharing anecdotes of his travels in Russian and Mongolia was less boring than waiting in his car. We had been waiting for ten hours and had not even entered the first checkpoint.

It was completely dark when the Latvian officials inspected our car and, twenty minutes later, let us move on to the Russians. The Russian portion of the border consists of a handful of checkpoints, checking passports, checking cars, checking papers…twice maybe, and for each checkpoint you wait. First you wait in a small group of cars to enter the checkpoint, then you wait for an official to finish with the car ahead of yours, then you might fill out a small bit of paper you didn’t know you had to have finished for the waiting official, then you wait to show them the bit of paper, and you wait nervously as someone frowns at your improvised scrawl in the Russian alphabet before saying something in their language and pointing toward imaginary Moscow. Then you drive 100 meters and do it again. One Russian official in a booth had a slight smile on her face as she checked our faces to our passports, at one in the morning perhaps enjoying the notion of the four of us youngsters taking on the widest country in the world, before stamping our passports and handing them back.

It took just that smooth forehead and up-turned corner of the mouth to tick our hopes into the positive quadrant, and we started finalizing our plan of attack – to spend the night in the car and drive to Moscow in the morning no matter how exhausted we might be. Ryan and Michael came back from yet another checkpoint, surely a formality at this point, with smiles on their faces after disappearing somewhere for 20 or 30 minutes. The news they had was perhaps the worst of our trip: no entry. Our temporary German vehicle registration was not enough to satisfy the Russians.

In those earliest morning hours we were basically halfway through the longest U-turn of any of our lives. We officially un-entered Russian and re-entered Latvia, meeting the same guards at the same stations we just labored through. We pulled into the same gas station rest stop we passed about 1 km from the border about 14 hours before, one with a bathroom so foul it deserves no description. We slept at awkward angles in our car seats, the dirty yellow creme in a Russian and Latvian semi-truck Oreo.

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